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Biochemistry-informed design selects potent siRNAs against SARS-CoV-2

RNA interference (RNAi) offers an efficient way to repress genes of interest, and it is widely used in research settings. Clinical applications emerged more recently, with 5 approved siRNAs (the RNA guides of the RNAi effector complex) against human diseases. The development of siRNAs against the SA...

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Detalles Bibliográficos
Autores principales:	Houbron, Élisabeth, Mockly, Sophie, Rafasse, Sophia, Gros, Nathalie, Muriaux, Delphine, Seitz, Hervé
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243379/ https://www.ncbi.nlm.nih.gov/pubmed/37272117 http://dx.doi.org/10.1080/15476286.2023.2217400

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