Production of the antidepressant orcinol glucoside in Yarrowia lipolytica with yields over 6,400-fold higher than plant extraction

Orcinol glucoside (OG), mainly found in the rhizome of the traditional Chinese herb Curculigo orchioides Gaertn, is noted for its antidepressant effects. In this study, an efficient screening pipeline was established for identifying the highly active orcinol synthase (ORS) and UDP-dependent glycosyl...

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Detalles Bibliográficos
Autores principales: Chen, Bihuan, Liu, Xiaonan, Wang, Yina, Bai, Jie, Liu, Xiangyu, Xiang, Guisheng, Liu, Wei, Zhu, Xiaoxi, Cheng, Jian, Lu, Lina, Zhang, Guanghui, Zhang, Ge, Dai, Zongjie, Zi, Shuhui, Yang, Shengchao, Jiang, Huifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243626/
https://www.ncbi.nlm.nih.gov/pubmed/37279234
http://dx.doi.org/10.1371/journal.pbio.3002131

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