β-Catenin signaling in alveolar macrophages enhances lung metastasis through a TNF-dependent mechanism

The main cause of malignancy-related mortality is metastasis. Although metastatic progression is driven by diverse tumor-intrinsic mechanisms, there is a growing appreciation for the contribution of tumor-extrinsic elements of the tumor microenvironment, especially macrophages, which correlate with...

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Detalles Bibliográficos
Autores principales: Kramer, Elliot D., Tzetzo, Stephanie L., Colligan, Sean H., Hensen, Mary L., Brackett, Craig M., Clausen, Björn E., Taketo, Makoto M., Abrams, Scott I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243816/
https://www.ncbi.nlm.nih.gov/pubmed/37092550
http://dx.doi.org/10.1172/jci.insight.160978

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