Microfluidic device facilitates in vitro modeling of human neonatal necrotizing enterocolitis–on-a-chip

Necrotizing enterocolitis (NEC) is a deadly gastrointestinal disease of premature infants that is associated with an exaggerated inflammatory response, dysbiosis of the gut microbiome, decreased epithelial cell proliferation, and gut barrier disruption. We describe an in vitro model of the human neo...

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Detalles Bibliográficos
Autores principales: Lanik, Wyatt E., Luke, Cliff J., Nolan, Lila S., Gong, Qingqing, Frazer, Lauren C., Rimer, Jamie M., Gale, Sarah E., Luc, Raymond, Bidani, Shay S., Sibbald, Carrie A., Lewis, Angela N., Mihi, Belgacem, Agrawal, Pranjal, Goree, Martin, Maestas, Marlie, Hu, Elise, Peters, David G., Good, Misty
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243823/
https://www.ncbi.nlm.nih.gov/pubmed/36881475
http://dx.doi.org/10.1172/jci.insight.146496

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