Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells

Invariant natural killer T (iNKT) cells act at the interface between lipid metabolism and immunity because of their restriction to lipid antigens presented on CD1d by antigen-presenting cells (APCs). How foreign lipid antigens are delivered to APCs remains elusive. Since lipoproteins routinely bind...

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Detalles Bibliográficos
Autores principales: Engelen, Suzanne E., Ververs, Francesca A., Markovska, Angela, Lagerholm, B. Christoffer, Kraaijenhof, Jordan M., Yousif, Laura I.E., Zurke, Yasemin-Xiomara, Gulersonmez, Can M.C., Kooijman, Sander, Goddard, Michael, van Eijkeren, Robert J., Jervis, Peter J., Besra, Gurdyal S., Haitjema, Saskia, Asselbergs, Folkert W., Kalkhoven, Eric, Ploegh, Hidde L., Boes, Marianne, Cerundolo, Vincenzo, Hovingh, G.K., Salio, Mariolina, Stigter, Edwin C.A., Rensen, Patrick C.N., Monaco, Claudia, Schipper, Henk S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243825/
https://www.ncbi.nlm.nih.gov/pubmed/36976644
http://dx.doi.org/10.1172/jci.insight.158089

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