RBM47 regulates intestinal injury and tumorigenesis by modifying proliferation, oxidative response, and inflammatory pathways

RNA-binding protein 47 (RBM47) is required for embryonic endoderm development, but a role in adult intestine is unknown. We studied intestine-specific Rbm47-knockout mice (Rbm47-IKO) following intestinal injury and made crosses into Apc(Min/+) mice to examine alterations in intestinal proliferation,...

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Detalles Bibliográficos
Autores principales: Soleymanjahi, Saeed, Blanc, Valerie, Molitor, Elizabeth A., Alvarado, David M., Xie, Yan, Gazit, Vered, Brown, Jeffrey W., Byrnes, Kathleen, Liu, Ta-Chiang, Mills, Jason C., Ciorba, Matthew A., Rubin, Deborah C., Davidson, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243830/
https://www.ncbi.nlm.nih.gov/pubmed/37014710
http://dx.doi.org/10.1172/jci.insight.161118

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