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Downregulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19

T cells play key protective but also pathogenic roles in COVID-19. We studied the expression of long non-coding RNAs (lncRNAs) in COVID-19 T-cell transcriptomes by integrating previously published single-cell RNA sequencing datasets. The long intergenic non-coding RNA MALAT1 was the most highly tran...

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Detalles Bibliográficos
Autores principales: Dey, Shoumit, Ashwin, Helen, Milross, Luke, Hunter, Bethany, Majo, Joaquim, Filby, Andrew J, Fisher, Andrew J, Kaye, Paul M, Lagos, Dimitris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243916/
https://www.ncbi.nlm.nih.gov/pubmed/36869729
http://dx.doi.org/10.1093/cei/uxad034