Cargando…

Downregulation of MALAT1 is a hallmark of tissue and peripheral proliferative T cells in COVID-19

T cells play key protective but also pathogenic roles in COVID-19. We studied the expression of long non-coding RNAs (lncRNAs) in COVID-19 T-cell transcriptomes by integrating previously published single-cell RNA sequencing datasets. The long intergenic non-coding RNA MALAT1 was the most highly tran...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dey, Shoumit, Ashwin, Helen, Milross, Luke, Hunter, Bethany, Majo, Joaquim, Filby, Andrew J, Fisher, Andrew J, Kaye, Paul M, Lagos, Dimitris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Infection/Infectious Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243916/ https://www.ncbi.nlm.nih.gov/pubmed/36869729 http://dx.doi.org/10.1093/cei/uxad034

Ejemplares similares

Identification of a protein expression signature distinguishing early from organising diffuse alveolar damage in COVID-19 patients
por: Ashwin, Helen, et al.
Publicado: (2023)

Post-mortem lung tissue: the fossil record of the pathophysiology and immunopathology of severe COVID-19
por: Milross, Luke, et al.
Publicado: (2022)

The trajectory of COVID-19 cardiopulmonary disease: insights from an autopsy study of community-based, pre-hospital deaths
por: Milross, Luke, et al.
Publicado: (2022)

Immune processes in the pathogenesis of chronic lung allograft dysfunction: identifying the missing pieces of the puzzle
por: Bos, Saskia, et al.
Publicado: (2022)

Mathematical modelling of activation-induced heterogeneity in TNF, IL6, NOS2, and IL1β expression reveals cell state transitions underpinning macrophage responses to LPS
por: Dey, Shoumit, et al.
Publicado: (2022)

Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells
por: Hewitson, James P., et al.
Publicado: (2020)

NITRIC OXIDE MAY SERVE AS A HALLMARK OF LONG COVID
por: WANG, J., et al.
Publicado: (2022)

Downregulation of semaphorin 3E promotes hallmarks of experimental chronic allergic asthma
por: Movassagh, Hesam, et al.
Publicado: (2017)

Kinetics of immune responses to SARS-CoV-2 proteins in individuals with varying severity of infection and following a single dose of the AZD1222
por: Jayathilaka, Deshni, et al.
Publicado: (2022)

SARS-CoV-2 infection is associated with anti-desmoglein 2 autoantibody detection
por: Ward, Kerensa E, et al.
Publicado: (2023)

Evaluation of QuantiFERON SARS-CoV-2 interferon-γ release assay following SARS-CoV-2 infection and vaccination
por: Johnson, Síle A, et al.
Publicado: (2023)

Low-Pressure Hydrocephalus in Spontaneous Angiogram-Negative Subarachnoid Hemorrhage Following COVID-19 Infection
por: Weisbrod, Luke, et al.
Publicado: (2021)

Mucormycosis of the Spine: A Case Report and Review of the Literature
por: Patel, Jaimin, et al.
Publicado: (2022)

Murine and Human Cathelicidins Contribute Differently to Hallmarks of Mastitis Induced by Pathogenic Prototheca bovis Algae
por: Shahid, Muhammad, et al.
Publicado: (2020)

Hallmarks of the relationship between host and Trypanosoma cruzi sulfated glycoconjugates along the course of Chagas disease
por: Soprano, Luciana L., et al.
Publicado: (2023)

Currently prescribed drugs in the UK that could upregulate or downregulate ACE2 in COVID-19 disease: a systematic review
por: Dambha-Miller, Hajira, et al.
Publicado: (2020)

Infection profile of immune-modulatory drugs used in autoimmune diseases: analysis of summary of product characteristic data
por: Dey, Mrinalini, et al.
Publicado: (2022)

Immunometabolic Analysis of Mobiluncus mulieris and Eggerthella sp. Reveals Novel Insights Into Their Pathogenic Contributions to the Hallmarks of Bacterial Vaginosis
por: McKenzie, Ross, et al.
Publicado: (2021)

Spatially Resolved Immunometabolism to Understand Infectious Disease Progression
por: Tans, Roel, et al.
Publicado: (2021)

Trypanosoma cruzi-specific CD8(+) T cells and other immunological hallmarks in chronic Chagas cardiomyopathy: Two decades of research
por: Puerta, Concepción J., et al.
Publicado: (2023)

Chromosomal Instability as Enabling Feature and Central Hallmark of Breast Cancer
por: Castellanos, Giovanny, et al.
Publicado: (2023)

Hallmarks of cancer and hallmarks of aging
por: Blagosklonny, Mikhail V.
Publicado: (2022)

Pan-cancer characterisation of microRNA across cancer hallmarks reveals microRNA-mediated downregulation of tumour suppressors
por: Dhawan, Andrew, et al.
Publicado: (2018)

Lyme Disease and Post-treatment Lyme Disease Syndrome: Current and Developing Treatment Options
por: Talbot, Norris C, et al.
Publicado: (2023)

miR-548d-3p Alters Parasite Growth and Inflammation in Leishmania (Viannia) braziliensis Infection
por: Souza, Marina de Assis, et al.
Publicado: (2021)

LCMV induced downregulation of HVEM on antiviral T cells is critical for an efficient effector response
por: Diethelm, Patrizia, et al.
Publicado: (2022)

miR-548d-3p Is Up-Regulated in Human Visceral Leishmaniasis and Suppresses Parasite Growth in Macrophages
por: Ramos-Sanchez, Eduardo Milton, et al.
Publicado: (2022)

Corrigendum: miR-548d-3p Is Up-regulated in Human Visceral Leishmaniasis and Suppresses Parasite Growth in Macrophages
por: Ramos-Sanchez, Eduardo Milton, et al.
Publicado: (2022)

IL-4 and helminth infection downregulate MINCLE-dependent macrophage response to mycobacteria and Th17 adjuvanticity
por: Schick, Judith, et al.
Publicado: (2023)

Secondary Hemophagocytic Lymphohistiocytosis in Post-COVID-19 Patients: A Report of Two Cases
por: Kalita, Pranjal, et al.
Publicado: (2021)

Low vaccination coverage of Greek Roma children amid economic crisis: national survey using stratified cluster sampling
por: Papamichail, Dimitris, et al.
Publicado: (2017)

Health care heroes?
por: DeLaney, Matthew, et al.
Publicado: (2021)

The Differences Between RSV and no RSV Acute Bronchiolitis in Hospitalized Infants: A Cross-Sectional Study
por: Christou, Evangelos, et al.
Publicado: (2022)

Protocol for the COG-UK hospital-onset COVID-19 infection (HOCI) multicentre interventional clinical study: evaluating the efficacy of rapid genome sequencing of SARS-CoV-2 in limiting the spread of COVID-19 in UK NHS hospitals
por: Blackstone, James, et al.
Publicado: (2022)

A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-β2 signaling
por: Mondal, Chandrani, et al.
Publicado: (2022)

Glycolysis downregulation is a hallmark of HIV‐1 latency and sensitizes infected cells to oxidative stress
por: Shytaj, Iart Luca, et al.
Publicado: (2021)

Expression of CFTR, a hallmark gene of ionocytes, is downregulated in salivary glands of Sjögren’s syndrome patients
por: Zhang, Qi, et al.
Publicado: (2022)

Downregulation of LRP/LR with siRNA inhibits several cancer hallmarks in lung cancer cells
por: Bignoux, Monique J., et al.
Publicado: (2023)

Challenges and Outcomes of COVID-19 Positive Neurosurgical Patients: An Institutional Experience With Emphasis on Modifications of Neurosurgical Practice
por: Singh, Binoy K, et al.
Publicado: (2021)

Seroprevalence and risk factors for toxoplasmosis among antenatal women in London: a re-examination of risk in an ethnically diverse population
por: Flatt, Andrew, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_fcjhgvbfvl357k4qat31am3dvq