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Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19

Persistent fever due to coronavirus disease 2019 (COVID-19) is a considerable issue for patients and physicians that requires a broad differential diagnosis and evaluation of complications. Coinfections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and various respiratory viruses...

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Autores principales: Ura, Kazuya, Goubaru, Yumi, Motoya, Misato, Ishii, Hidehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243944/
https://www.ncbi.nlm.nih.gov/pubmed/37288151
http://dx.doi.org/10.1155/2023/6684783
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author Ura, Kazuya
Goubaru, Yumi
Motoya, Misato
Ishii, Hidehiro
author_facet Ura, Kazuya
Goubaru, Yumi
Motoya, Misato
Ishii, Hidehiro
author_sort Ura, Kazuya
collection PubMed
description Persistent fever due to coronavirus disease 2019 (COVID-19) is a considerable issue for patients and physicians that requires a broad differential diagnosis and evaluation of complications. Coinfections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and various respiratory viruses have also been reported. In severe cases of COVID-19, cytomegalovirus (CMV) reactivation or CMV coinfection with SARS-CoV-2 has been reported in association with critical illnesses and immunosuppressive therapy; however, in mild COVID-19 cases, CMV coinfection with SARS-CoV-2 has been reported only in severely immunocompromised patients, and its incidence and clinical importance remain unclear. Herein, we report a rare case of coinfection with SARS-CoV-2 and CMV in a patient with mild COVID-19 and untreated diabetes mellitus, which led to persistent fever for approximately 4 weeks. CMV coinfection should be considered in patients with COVID-19 who exhibit persistent fever.
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spelling pubmed-102439442023-06-07 Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19 Ura, Kazuya Goubaru, Yumi Motoya, Misato Ishii, Hidehiro Case Rep Infect Dis Case Report Persistent fever due to coronavirus disease 2019 (COVID-19) is a considerable issue for patients and physicians that requires a broad differential diagnosis and evaluation of complications. Coinfections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and various respiratory viruses have also been reported. In severe cases of COVID-19, cytomegalovirus (CMV) reactivation or CMV coinfection with SARS-CoV-2 has been reported in association with critical illnesses and immunosuppressive therapy; however, in mild COVID-19 cases, CMV coinfection with SARS-CoV-2 has been reported only in severely immunocompromised patients, and its incidence and clinical importance remain unclear. Herein, we report a rare case of coinfection with SARS-CoV-2 and CMV in a patient with mild COVID-19 and untreated diabetes mellitus, which led to persistent fever for approximately 4 weeks. CMV coinfection should be considered in patients with COVID-19 who exhibit persistent fever. Hindawi 2023-05-30 /pmc/articles/PMC10243944/ /pubmed/37288151 http://dx.doi.org/10.1155/2023/6684783 Text en Copyright © 2023 Kazuya Ura et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ura, Kazuya
Goubaru, Yumi
Motoya, Misato
Ishii, Hidehiro
Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title_full Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title_fullStr Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title_full_unstemmed Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title_short Coinfection with SARS-CoV-2 and Cytomegalovirus in a Patient with Mild COVID-19
title_sort coinfection with sars-cov-2 and cytomegalovirus in a patient with mild covid-19
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243944/
https://www.ncbi.nlm.nih.gov/pubmed/37288151
http://dx.doi.org/10.1155/2023/6684783
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