Isocitrate dehydrogenase mutations in gliomas: A review of current understanding and trials

Isocitrate dehydrogenase (IDH) is a key enzyme in normal metabolism and homeostasis. However, mutant forms of IDH are also defining features of a subset of diffuse gliomas. In this review, we highlight current techniques targeting IDH-mutated gliomas and summarize current and completed clinical tria...

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Detalles Bibliográficos
Autores principales: Sharma, Nikhil, Mallela, Arka N, Shi, Diana D, Tang, Lilly W, Abou-Al-Shaar, Hussam, Gersey, Zachary C, Zhang, Xiaoran, McBrayer, Samuel K, Abdullah, Kalil G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243983/
https://www.ncbi.nlm.nih.gov/pubmed/37287696
http://dx.doi.org/10.1093/noajnl/vdad053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10243983/
https://www.ncbi.nlm.nih.gov/pubmed/37287696
http://dx.doi.org/10.1093/noajnl/vdad053

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