TYMS promotes genomic instability and tumor progression in Ink4a/Arf null background

We previously showed that elevated TYMS exhibits oncogenic properties and promotes tumorigenesis after a long latency, suggesting cooperation with sequential somatic mutations. Here we report the cooperation of ectopic expression of human TYMS with loss of Ink4a/Arf, one of the most commonly mutated...

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Detalles Bibliográficos
Autores principales: Guijarro, Maria V., Nawab, Akbar, Dib, Peter, Burkett, Sandra, Luo, Xiaoping, Feely, Michael, Nasri, Elham, Seifert, Robert P., Kaye, Frederic J., Zajac-Kaye, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244171/
https://www.ncbi.nlm.nih.gov/pubmed/37106126
http://dx.doi.org/10.1038/s41388-023-02694-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244171/
https://www.ncbi.nlm.nih.gov/pubmed/37106126
http://dx.doi.org/10.1038/s41388-023-02694-7

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