Investigating causality in the association between DNA methylation and type 2 diabetes using bidirectional two-sample Mendelian randomisation

AIMS/HYPOTHESIS: Several studies have identified associations between type 2 diabetes and DNA methylation (DNAm). However, the causal role of these associations remains unclear. This study aimed to provide evidence for a causal relationship between DNAm and type 2 diabetes. METHODS: We used bidirect...

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Detalles Bibliográficos
Autores principales: Juvinao-Quintero, Diana L., Sharp, Gemma C., Sanderson, Eleanor C. M., Relton, Caroline L., Elliott, Hannah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244277/
https://www.ncbi.nlm.nih.gov/pubmed/37202507
http://dx.doi.org/10.1007/s00125-023-05914-7

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