NERNST: a genetically-encoded ratiometric non-destructive sensing tool to estimate NADP(H) redox status in bacterial, plant and animal systems

NADP(H) is a central metabolic hub providing reducing equivalents to multiple biosynthetic, regulatory and antioxidative pathways in all living organisms. While biosensors are available to determine NADP(+) or NADPH levels in vivo, no probe exists to estimate the NADP(H) redox status, a determinant...

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Detalles Bibliográficos
Autores principales: Molinari, Pamela E., Krapp, Adriana R., Weiner, Andrea, Beyer, Hannes M., Kondadi, Arun Kumar, Blomeier, Tim, López, Melina, Bustos-Sanmamed, Pilar, Tevere, Evelyn, Weber, Wilfried, Reichert, Andreas S., Calcaterra, Nora B., Beller, Mathias, Carrillo, Nestor, Zurbriggen, Matias D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244373/
https://www.ncbi.nlm.nih.gov/pubmed/37280202
http://dx.doi.org/10.1038/s41467-023-38739-4

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