Cargando…
Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3
A growing body of evidence suggests that oxysterols such as 25-hydroxycholesterol (25HC) are biologically active and involved in many physiological and pathological processes. Our previous study demonstrated that 25HC induces an innate immune response during viral infections by activating the integr...
Autores principales: | Gc, Jeevan B., Chen, Justin, Pokharel, Swechha M., Mohanty, Indira, Mariasoosai, Charles, Obi, Peter, Panipinto, Paul, Bandyopadhyay, Smarajit, Bose, Santanu, Natesan, Senthil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244445/ https://www.ncbi.nlm.nih.gov/pubmed/37280310 http://dx.doi.org/10.1038/s41598-023-36040-4 |
Ejemplares similares
-
Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response
por: Pokharel, Swechha M., et al.
Publicado: (2019) -
Human beta defensin-3 mediated activation of β-catenin during human respiratory syncytial virus infection: interaction of HBD3 with LDL receptor-related protein 5
por: Pokharel, Swechha M., et al.
Publicado: (2023) -
Tumor Necrosis Factor-alpha utilizes MAPK/NFκB pathways to induce cholesterol-25 hydroxylase for amplifying pro-inflammatory response via 25-hydroxycholesterol-integrin-FAK pathway
por: Pokharel, Swechha M., et al.
Publicado: (2021) -
Lytic Cell Death Mechanisms in Human Respiratory Syncytial Virus-Infected Macrophages: Roles of Pyroptosis and Necroptosis
por: Bedient, Lori, et al.
Publicado: (2020) -
Autophagy, TGF-β, and SMAD-2/3 Signaling Regulates Interferon-β Response in Respiratory Syncytial Virus Infected Macrophages
por: Pokharel, Swechha M., et al.
Publicado: (2016)