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Drug screening at single-organoid resolution via bioprinting and interferometry

High throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clinically relevant model systems such as three-dimensional tumo...

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Detalles Bibliográficos
Autores principales: Tebon, Peyton J., Wang, Bowen, Markowitz, Alexander L., Davarifar, Ardalan, Tsai, Brandon L., Krawczuk, Patrycja, Gonzalez, Alfredo E., Sartini, Sara, Murray, Graeme F., Nguyen, Huyen Thi Lam, Tavanaie, Nasrin, Nguyen, Thang L., Boutros, Paul C., Teitell, Michael A., Soragni, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244450/
https://www.ncbi.nlm.nih.gov/pubmed/37280220
http://dx.doi.org/10.1038/s41467-023-38832-8