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Drug screening at single-organoid resolution via bioprinting and interferometry
High throughput drug screening is an established approach to investigate tumor biology and identify therapeutic leads. Traditional platforms use two-dimensional cultures which do not accurately reflect the biology of human tumors. More clinically relevant model systems such as three-dimensional tumo...
Autores principales: | Tebon, Peyton J., Wang, Bowen, Markowitz, Alexander L., Davarifar, Ardalan, Tsai, Brandon L., Krawczuk, Patrycja, Gonzalez, Alfredo E., Sartini, Sara, Murray, Graeme F., Nguyen, Huyen Thi Lam, Tavanaie, Nasrin, Nguyen, Thang L., Boutros, Paul C., Teitell, Michael A., Soragni, Alice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244450/ https://www.ncbi.nlm.nih.gov/pubmed/37280220 http://dx.doi.org/10.1038/s41467-023-38832-8 |
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