The TRAF2-p62 axis promotes proliferation and survival of liver cancer by activating mTORC1 pathway

TRAF2 (Tumor necrosis factor receptor-associated factor 2) is a dual function protein, acting as an adaptor protein and a ubiquitin E3 ligase, which plays an essential role in mediating the TNFα-NFκB signal pathway. Dysregulated expression of TRAF2 has been reported in a variety of human cancers. Wh...

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Detalles Bibliográficos
Autores principales: Liang, Xue, Yao, Jiping, Cui, Danrui, Zheng, Weiyang, Liu, Yanning, Lou, Guohua, Ye, Bingjue, Shui, Liyan, Sun, Yi, Zhao, Yongchao, Zheng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244464/
https://www.ncbi.nlm.nih.gov/pubmed/37081115
http://dx.doi.org/10.1038/s41418-023-01164-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244464/
https://www.ncbi.nlm.nih.gov/pubmed/37081115
http://dx.doi.org/10.1038/s41418-023-01164-7

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