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Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet

Acoustic neuroma is one of the most common tumors in the cerebellopontine angle area. Patients with acoustic neuroma have clinical manifestations of the cerebellopontine angle occupying syndrome, such as tinnitus, hearing impairment and even hearing loss. Acoustic neuromas often grow in the internal...

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Autores principales: Zhang, Zhuo, Zhang, Xiaochen, Yang, Yong, Liu, Jieyu, Zheng, Chenzi, Bai, Hua, Ma, Quanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244508/
https://www.ncbi.nlm.nih.gov/pubmed/37292160
http://dx.doi.org/10.3389/fnins.2023.1207149
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author Zhang, Zhuo
Zhang, Xiaochen
Yang, Yong
Liu, Jieyu
Zheng, Chenzi
Bai, Hua
Ma, Quanfeng
author_facet Zhang, Zhuo
Zhang, Xiaochen
Yang, Yong
Liu, Jieyu
Zheng, Chenzi
Bai, Hua
Ma, Quanfeng
author_sort Zhang, Zhuo
collection PubMed
description Acoustic neuroma is one of the most common tumors in the cerebellopontine angle area. Patients with acoustic neuroma have clinical manifestations of the cerebellopontine angle occupying syndrome, such as tinnitus, hearing impairment and even hearing loss. Acoustic neuromas often grow in the internal auditory canal. Neurosurgeons need to observe the lesion contour with the help of MRI images, which not only takes a lot of time, but also is easily affected by subjective factors. Therefore, the automatic and accurate segmentation of acoustic neuroma in cerebellopontine angle on MRI is of great significance for surgical treatment and expected rehabilitation. In this paper, an automatic segmentation method based on Transformer is proposed, using TransUNet as the core model. As some acoustic neuromas are irregular in shape and grow into the internal auditory canal, larger receptive fields are thus needed to synthesize the features. Therefore, we added Atrous Spatial Pyramid Pooling to CNN, which can obtain a larger receptive field without losing too much resolution. Since acoustic neuromas often occur in the cerebellopontine angle area with relatively fixed position, we combined channel attention with pixel attention in the up-sampling stage so as to make our model automatically learn different weights by adding the attention mechanism. In addition, we collected 300 MRI sequence nuclear resonance images of patients with acoustic neuromas in Tianjin Huanhu hospital for training and verification. The ablation experimental results show that the proposed method is reasonable and effective. The comparative experimental results show that the Dice and Hausdorff 95 metrics of the proposed method reach 95.74% and 1.9476 mm respectively, indicating that it is not only superior to the classical models such as UNet, PANet, PSPNet, UNet++, and DeepLabv3, but also show better performance than the newly-proposed SOTA (state-of-the-art) models such as CCNet, MANet, BiseNetv2, Swin-Unet, MedT, TransUNet, and UCTransNet.
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spelling pubmed-102445082023-06-08 Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet Zhang, Zhuo Zhang, Xiaochen Yang, Yong Liu, Jieyu Zheng, Chenzi Bai, Hua Ma, Quanfeng Front Neurosci Neuroscience Acoustic neuroma is one of the most common tumors in the cerebellopontine angle area. Patients with acoustic neuroma have clinical manifestations of the cerebellopontine angle occupying syndrome, such as tinnitus, hearing impairment and even hearing loss. Acoustic neuromas often grow in the internal auditory canal. Neurosurgeons need to observe the lesion contour with the help of MRI images, which not only takes a lot of time, but also is easily affected by subjective factors. Therefore, the automatic and accurate segmentation of acoustic neuroma in cerebellopontine angle on MRI is of great significance for surgical treatment and expected rehabilitation. In this paper, an automatic segmentation method based on Transformer is proposed, using TransUNet as the core model. As some acoustic neuromas are irregular in shape and grow into the internal auditory canal, larger receptive fields are thus needed to synthesize the features. Therefore, we added Atrous Spatial Pyramid Pooling to CNN, which can obtain a larger receptive field without losing too much resolution. Since acoustic neuromas often occur in the cerebellopontine angle area with relatively fixed position, we combined channel attention with pixel attention in the up-sampling stage so as to make our model automatically learn different weights by adding the attention mechanism. In addition, we collected 300 MRI sequence nuclear resonance images of patients with acoustic neuromas in Tianjin Huanhu hospital for training and verification. The ablation experimental results show that the proposed method is reasonable and effective. The comparative experimental results show that the Dice and Hausdorff 95 metrics of the proposed method reach 95.74% and 1.9476 mm respectively, indicating that it is not only superior to the classical models such as UNet, PANet, PSPNet, UNet++, and DeepLabv3, but also show better performance than the newly-proposed SOTA (state-of-the-art) models such as CCNet, MANet, BiseNetv2, Swin-Unet, MedT, TransUNet, and UCTransNet. Frontiers Media S.A. 2023-05-24 /pmc/articles/PMC10244508/ /pubmed/37292160 http://dx.doi.org/10.3389/fnins.2023.1207149 Text en Copyright © 2023 Zhang, Zhang, Yang, Liu, Zheng, Bai and Ma. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Zhang, Zhuo
Zhang, Xiaochen
Yang, Yong
Liu, Jieyu
Zheng, Chenzi
Bai, Hua
Ma, Quanfeng
Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title_full Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title_fullStr Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title_full_unstemmed Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title_short Accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on ACP-TransUNet
title_sort accurate segmentation algorithm of acoustic neuroma in the cerebellopontine angle based on acp-transunet
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244508/
https://www.ncbi.nlm.nih.gov/pubmed/37292160
http://dx.doi.org/10.3389/fnins.2023.1207149
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