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Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report
Usual interstitial pneumonia is the most common type of microscopic polyangiitis (MPA)-associated interstitial lung disease, and patients may initially present with isolated pulmonary fibrosis, which often leads to a misdiagnosis of idiopathic pulmonary fibrosis (IPF). Here, we describe a patient wh...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244548/ https://www.ncbi.nlm.nih.gov/pubmed/37293302 http://dx.doi.org/10.3389/fmed.2023.1157922 |
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author | Shao, Chi Chen, Ruxuan Huang, Hui Zhao, Yang Chen, Keqi Xu, Kai |
author_facet | Shao, Chi Chen, Ruxuan Huang, Hui Zhao, Yang Chen, Keqi Xu, Kai |
author_sort | Shao, Chi |
collection | PubMed |
description | Usual interstitial pneumonia is the most common type of microscopic polyangiitis (MPA)-associated interstitial lung disease, and patients may initially present with isolated pulmonary fibrosis, which often leads to a misdiagnosis of idiopathic pulmonary fibrosis (IPF). Here, we describe a patient who developed fever of unknown origin, microscopic hematuria and renal insufficiency, who then tested positive for antineutrophil cytoplasmic antibody (ANCA) and was diagnosed with MPA after receiving antifibrotic medication for IPF (original diagnosis) for almost 10 years. The patient's symptoms were ameliorated after administration of additional glucocorticoids and immunosuppressants. |
format | Online Article Text |
id | pubmed-10244548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102445482023-06-08 Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report Shao, Chi Chen, Ruxuan Huang, Hui Zhao, Yang Chen, Keqi Xu, Kai Front Med (Lausanne) Medicine Usual interstitial pneumonia is the most common type of microscopic polyangiitis (MPA)-associated interstitial lung disease, and patients may initially present with isolated pulmonary fibrosis, which often leads to a misdiagnosis of idiopathic pulmonary fibrosis (IPF). Here, we describe a patient who developed fever of unknown origin, microscopic hematuria and renal insufficiency, who then tested positive for antineutrophil cytoplasmic antibody (ANCA) and was diagnosed with MPA after receiving antifibrotic medication for IPF (original diagnosis) for almost 10 years. The patient's symptoms were ameliorated after administration of additional glucocorticoids and immunosuppressants. Frontiers Media S.A. 2023-05-24 /pmc/articles/PMC10244548/ /pubmed/37293302 http://dx.doi.org/10.3389/fmed.2023.1157922 Text en Copyright © 2023 Shao, Chen, Huang, Zhao, Chen and Xu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Shao, Chi Chen, Ruxuan Huang, Hui Zhao, Yang Chen, Keqi Xu, Kai Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title | Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title_full | Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title_fullStr | Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title_full_unstemmed | Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title_short | Microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
title_sort | microscopic polyangiitis initially presenting with idiopathic pulmonary fibrosis: a case report |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244548/ https://www.ncbi.nlm.nih.gov/pubmed/37293302 http://dx.doi.org/10.3389/fmed.2023.1157922 |
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