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Concerted suppressive effects of carisbamate, an anti-epileptic alkyl-carbamate drug, on voltage-gated Na(+) and hyperpolarization-activated cation currents

Carisbamate (CRS, RWJ-333369) is a new anti-seizure medication. It remains unclear whether and how CRS can perturb the magnitude and/or gating kinetics of membrane ionic currents, despite a few reports demonstrating its ability to suppress voltage-gated Na(+) currents. In this study, we observed a s...

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Detalles Bibliográficos
Autores principales:	Hung, Te-Yu, Wu, Sheng-Nan, Huang, Chin-Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244622/ https://www.ncbi.nlm.nih.gov/pubmed/37293624 http://dx.doi.org/10.3389/fncel.2023.1159067

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