In vivo(18)F-DOPA PET imaging identifies a dopaminergic deficit in a rat model with a G51D α-synuclein mutation

Parkinson’s disease (PD) is a neurodegenerative condition with several major hallmarks, including loss of substantia nigra neurons, reduction in striatal dopaminergic function, and formation of α-synuclein-rich Lewy bodies. Mutations in SNCA, encoding for α-synuclein, are a known cause of familial P...

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Detalles Bibliográficos
Autores principales: Morley, Victoria, Dolt, Karamjit Singh, Alcaide-Corral, Carlos J., Walton, Tashfeen, Lucatelli, Christophe, Mashimo, Tomoji, Tavares, Adriana A. S., Kunath, Tilo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244711/
https://www.ncbi.nlm.nih.gov/pubmed/37292159
http://dx.doi.org/10.3389/fnins.2023.1095761

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244711/
https://www.ncbi.nlm.nih.gov/pubmed/37292159
http://dx.doi.org/10.3389/fnins.2023.1095761

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