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Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria
BACKGROUND: The parasite Schistosoma haematobium causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children. OBJECTIVE: The prevalence of S. haematobium infection and level of intensity relative to age, gender and status of selected serum micronutrie...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AOSIS
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244817/ https://www.ncbi.nlm.nih.gov/pubmed/37293318 http://dx.doi.org/10.4102/ajlm.v12i1.2034 |
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author | Olerimi, Samson E. Ekhoye, Ehitare I. Enaiho, Oriasotie S. Olerimi, Alexander |
author_facet | Olerimi, Samson E. Ekhoye, Ehitare I. Enaiho, Oriasotie S. Olerimi, Alexander |
author_sort | Olerimi, Samson E. |
collection | PubMed |
description | BACKGROUND: The parasite Schistosoma haematobium causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children. OBJECTIVE: The prevalence of S. haematobium infection and level of intensity relative to age, gender and status of selected serum micronutrients among school-age children were investigated in suburban communities in Bekwarra, Nigeria. METHODS: This cross-sectional school-based study randomly recruited 353 children aged between 4 and 16 years from five elementary schools between June 2019 and December 2019. We gathered socio-demographic data about each child using a semi-structured questionnaire. Blood samples were collected for micronutrient analysis and urine samples were collected for assessment of S. haematobium infection. RESULTS: A total of 57 (16.15%) school-age children were infected with S. haematobium. Girls (n = 34; 9.63%) were more frequently infected than boys (n = 23; 6.52%). Infection was most frequent among children aged 8–11 years (n = 32; 23.19%) and was significantly associated with age (p = 0.022) and gender (p < 0.001). Serum levels of iron, calcium, copper and zinc among infected children were significantly lower than those of non-infected children. Intensity of infection was negatively associated with iron (r = −0.21), calcium (r = −0.24), copper (r = −0.61; p < 0.001) and zinc (r = −0.41; p < 0.002). CONCLUSION: This study showed that S. haematobium infection adversely impacted the micronutrient status of school-age children in suburban Nigeria. Measures to lower the prevalence of schistosomiasis among school-age children, including efficient drug distribution, education campaigns and community engagement, are necessary. WHAT THIS STUDY ADDS: This research emphasises the significance of implementing infection prevention and control interventions to mitigate the transmission and prevalence of schistosomiasis among school age children. |
format | Online Article Text |
id | pubmed-10244817 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | AOSIS |
record_format | MEDLINE/PubMed |
spelling | pubmed-102448172023-06-08 Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria Olerimi, Samson E. Ekhoye, Ehitare I. Enaiho, Oriasotie S. Olerimi, Alexander Afr J Lab Med Original Research BACKGROUND: The parasite Schistosoma haematobium causes urogenital schistosomiasis, a chronic infectious disease that occurs mainly among school-age children. OBJECTIVE: The prevalence of S. haematobium infection and level of intensity relative to age, gender and status of selected serum micronutrients among school-age children were investigated in suburban communities in Bekwarra, Nigeria. METHODS: This cross-sectional school-based study randomly recruited 353 children aged between 4 and 16 years from five elementary schools between June 2019 and December 2019. We gathered socio-demographic data about each child using a semi-structured questionnaire. Blood samples were collected for micronutrient analysis and urine samples were collected for assessment of S. haematobium infection. RESULTS: A total of 57 (16.15%) school-age children were infected with S. haematobium. Girls (n = 34; 9.63%) were more frequently infected than boys (n = 23; 6.52%). Infection was most frequent among children aged 8–11 years (n = 32; 23.19%) and was significantly associated with age (p = 0.022) and gender (p < 0.001). Serum levels of iron, calcium, copper and zinc among infected children were significantly lower than those of non-infected children. Intensity of infection was negatively associated with iron (r = −0.21), calcium (r = −0.24), copper (r = −0.61; p < 0.001) and zinc (r = −0.41; p < 0.002). CONCLUSION: This study showed that S. haematobium infection adversely impacted the micronutrient status of school-age children in suburban Nigeria. Measures to lower the prevalence of schistosomiasis among school-age children, including efficient drug distribution, education campaigns and community engagement, are necessary. WHAT THIS STUDY ADDS: This research emphasises the significance of implementing infection prevention and control interventions to mitigate the transmission and prevalence of schistosomiasis among school age children. AOSIS 2023-05-31 /pmc/articles/PMC10244817/ /pubmed/37293318 http://dx.doi.org/10.4102/ajlm.v12i1.2034 Text en © 2023. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License. |
spellingShingle | Original Research Olerimi, Samson E. Ekhoye, Ehitare I. Enaiho, Oriasotie S. Olerimi, Alexander Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title | Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title_full | Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title_fullStr | Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title_full_unstemmed | Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title_short | Selected micronutrient status of school-aged children at risk of Schistosoma haematobium infection in suburban communities of Nigeria |
title_sort | selected micronutrient status of school-aged children at risk of schistosoma haematobium infection in suburban communities of nigeria |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244817/ https://www.ncbi.nlm.nih.gov/pubmed/37293318 http://dx.doi.org/10.4102/ajlm.v12i1.2034 |
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