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Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4(CreERT2) versus Aggrecan(CreERT2) transgene in mice
BACKGROUND: Genetically modified mice are the most useful tools for investigating the gene functions in articular cartilage biology and the pathogenesis of osteoarthritis. The Aggrecan(CreERT2) mice are one of the most reported mouse lines used for this purpose. The Prg4 (proteoglycan 4) gene encode...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Chinese Speaking Orthopaedic Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244901/ https://www.ncbi.nlm.nih.gov/pubmed/37292436 http://dx.doi.org/10.1016/j.jot.2023.05.005 |