Comparison of Kindlin-2 deficiency-stimulated osteoarthritis-like lesions induced by Prg4(CreERT2) versus Aggrecan(CreERT2) transgene in mice

BACKGROUND: Genetically modified mice are the most useful tools for investigating the gene functions in articular cartilage biology and the pathogenesis of osteoarthritis. The Aggrecan(CreERT2) mice are one of the most reported mouse lines used for this purpose. The Prg4 (proteoglycan 4) gene encode...

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Detalles Bibliográficos
Autores principales: Yao, Qing, Gong, Weiyuan, Wu, Xiaohao, Gan, Donghao, Tao, Chu, Lin, Sixiong, Qu, Minghao, Ouyang, Zhongtian, Chen, Mingjue, Hu, Xinjia, Xiao, Guozhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244901/
https://www.ncbi.nlm.nih.gov/pubmed/37292436
http://dx.doi.org/10.1016/j.jot.2023.05.005

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