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Bone marrow mesenchymal stem cell transplantation alleviates radiation-induced myocardial fibrosis through inhibition of the TGF-β1/Smad2/3 signaling pathway in rabbit model

BACKGROUND: and purpose: Radiotherapy (RT) is an effective treatment for most malignant chest tumors. However, radiation-induced myocardial fibrosis (RIMF) is a serious side effect of RT. Currently, due to the mechanism of RIMF has not been fully elucidated, there is a lack of effective therapeutic...

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Detalles Bibliográficos
Autores principales: Gu, Jian Jun, Li, Hong Xiao, Wei, Wei, Sun, Xiao Lin, Li, Bi Chun, Chen, Yong, Li, Jun, Gu, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244902/
https://www.ncbi.nlm.nih.gov/pubmed/37292187
http://dx.doi.org/10.1016/j.reth.2023.04.003