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Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review
The purpose of this systematic review was to critically evaluate the available clinical literature on the use of regenerative endodontic therapy (RET) for the treatment of root resorption. All case reports, case series and clinical studies documenting the management of root resorption in mature or i...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Kare Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244915/ https://www.ncbi.nlm.nih.gov/pubmed/37257034 http://dx.doi.org/10.14744/eej.2023.77486 |
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author | Dadpe, Ashwini Manish Shah, Dipali Yogesh Natanasabapathy, Velmurugan Sureshbabu, Nivedhitha Malli Hindlekar, Ajit Narayan Modi, Kajal |
author_facet | Dadpe, Ashwini Manish Shah, Dipali Yogesh Natanasabapathy, Velmurugan Sureshbabu, Nivedhitha Malli Hindlekar, Ajit Narayan Modi, Kajal |
author_sort | Dadpe, Ashwini Manish |
collection | PubMed |
description | The purpose of this systematic review was to critically evaluate the available clinical literature on the use of regenerative endodontic therapy (RET) for the treatment of root resorption. All case reports, case series and clinical studies documenting the management of root resorption in mature or immature permanent teeth using RET were included. Review articles, animal studies, and RET in teeth showing developmental anomalies were excluded. A literature search was conducted in electronic databases MEDLINE, Scopus, Cochrane, and Google Scholar from 2001 to January 2022. The JBI Critical Appraisal Checklist Quality was used to appraise the included case reports and case series. The Methodological item for non-randomised studies (MINORS) tool was used to appraise the clinical study critically. After applying the inclusion and exclusion criteria, the search resulted in 14 studies (12 case reports, 1 case series, and 1 clinical study) accounting for root resorption in 34 teeth from 29 patients treated with RET. Despite the wide variation in RET protocols, the arrest of root resorption and resolution of symptoms was seen in all teeth except one (failure after 27 months). The clinical study’s cone beam computed tomography (CBCT) imaging evaluation documented a significant volumetric decrease in resorptive and periapical lesions after RET. The clinical study was deemed as good quality using the MINORS scale. The JBI critical appraisal tool showed that the case series was of poor quality; 11 of the case reports were of good quality, while 1 case report was of fair quality. This systematic review revealed a low-to-moderate level of evidence for the use of RET in resorption cases. However, further well-designed, long-term clinical studies are required to recommend it as an alternative treatment option for root resorption management. Funding: None. The systematic review was registered in PROSPERO (CRD42021274569). |
format | Online Article Text |
id | pubmed-10244915 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Kare Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-102449152023-06-08 Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review Dadpe, Ashwini Manish Shah, Dipali Yogesh Natanasabapathy, Velmurugan Sureshbabu, Nivedhitha Malli Hindlekar, Ajit Narayan Modi, Kajal Eur Endod J Systematic Review The purpose of this systematic review was to critically evaluate the available clinical literature on the use of regenerative endodontic therapy (RET) for the treatment of root resorption. All case reports, case series and clinical studies documenting the management of root resorption in mature or immature permanent teeth using RET were included. Review articles, animal studies, and RET in teeth showing developmental anomalies were excluded. A literature search was conducted in electronic databases MEDLINE, Scopus, Cochrane, and Google Scholar from 2001 to January 2022. The JBI Critical Appraisal Checklist Quality was used to appraise the included case reports and case series. The Methodological item for non-randomised studies (MINORS) tool was used to appraise the clinical study critically. After applying the inclusion and exclusion criteria, the search resulted in 14 studies (12 case reports, 1 case series, and 1 clinical study) accounting for root resorption in 34 teeth from 29 patients treated with RET. Despite the wide variation in RET protocols, the arrest of root resorption and resolution of symptoms was seen in all teeth except one (failure after 27 months). The clinical study’s cone beam computed tomography (CBCT) imaging evaluation documented a significant volumetric decrease in resorptive and periapical lesions after RET. The clinical study was deemed as good quality using the MINORS scale. The JBI critical appraisal tool showed that the case series was of poor quality; 11 of the case reports were of good quality, while 1 case report was of fair quality. This systematic review revealed a low-to-moderate level of evidence for the use of RET in resorption cases. However, further well-designed, long-term clinical studies are required to recommend it as an alternative treatment option for root resorption management. Funding: None. The systematic review was registered in PROSPERO (CRD42021274569). Kare Publishing 2023-05-15 /pmc/articles/PMC10244915/ /pubmed/37257034 http://dx.doi.org/10.14744/eej.2023.77486 Text en © Copyright 2023 by European Endodontic Journal https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/) |
spellingShingle | Systematic Review Dadpe, Ashwini Manish Shah, Dipali Yogesh Natanasabapathy, Velmurugan Sureshbabu, Nivedhitha Malli Hindlekar, Ajit Narayan Modi, Kajal Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title | Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title_full | Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title_fullStr | Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title_full_unstemmed | Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title_short | Regenerative Endodontic Procedures in Teeth with Root Resorption:A Systematic Review |
title_sort | regenerative endodontic procedures in teeth with root resorption:a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244915/ https://www.ncbi.nlm.nih.gov/pubmed/37257034 http://dx.doi.org/10.14744/eej.2023.77486 |
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