Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal

We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adheren...

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Detalles Bibliográficos
Autores principales: Malinga, Sibongiseni, Khan, Aabida, Archary, Moherndran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244928/
https://www.ncbi.nlm.nih.gov/pubmed/37293603
http://dx.doi.org/10.4102/sajhivmed.v24i1.1458
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author Malinga, Sibongiseni
Khan, Aabida
Archary, Moherndran
author_facet Malinga, Sibongiseni
Khan, Aabida
Archary, Moherndran
author_sort Malinga, Sibongiseni
collection PubMed
description We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens.
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spelling pubmed-102449282023-06-08 Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal Malinga, Sibongiseni Khan, Aabida Archary, Moherndran South Afr J HIV Med Case Report We report a case of dolutegravir resistance in KwaZulu-Natal in a 13-year-old male two years after starting dolutegravir. Resistance most likely developed due to poor adherence as a result of psychosocial issues. This case highlights the importance of the role of the family unit in impacting adherence and close monitoring of treatment-experienced patients with virologic failure following switching to dolutegravir-based regimens. AOSIS 2023-05-23 /pmc/articles/PMC10244928/ /pubmed/37293603 http://dx.doi.org/10.4102/sajhivmed.v24i1.1458 Text en © 2023. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Case Report
Malinga, Sibongiseni
Khan, Aabida
Archary, Moherndran
Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title_full Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title_fullStr Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title_full_unstemmed Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title_short Breaking the unbreakable: A paediatric case of dolutegravir resistance from KwaZulu-Natal
title_sort breaking the unbreakable: a paediatric case of dolutegravir resistance from kwazulu-natal
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244928/
https://www.ncbi.nlm.nih.gov/pubmed/37293603
http://dx.doi.org/10.4102/sajhivmed.v24i1.1458
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AT archarymoherndran breakingtheunbreakableapaediatriccaseofdolutegravirresistancefromkwazulunatal

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