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Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital

BACKGROUND: Worldwide, intracranial aneurysms are associated with a high mortality rate. While endovascular management has proven to be the choice of treatment in selected patients, patient demographics and aneurysm characteristics differ between study populations. OBJECTIVES: This study aimed to in...

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Autores principales: Clarke, Herchel, Nefale, Trevor, Mngomezulu, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AOSIS 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244967/
https://www.ncbi.nlm.nih.gov/pubmed/37292418
http://dx.doi.org/10.4102/sajr.v27i1.2634
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author Clarke, Herchel
Nefale, Trevor
Mngomezulu, Victor
author_facet Clarke, Herchel
Nefale, Trevor
Mngomezulu, Victor
author_sort Clarke, Herchel
collection PubMed
description BACKGROUND: Worldwide, intracranial aneurysms are associated with a high mortality rate. While endovascular management has proven to be the choice of treatment in selected patients, patient demographics and aneurysm characteristics differ between study populations. OBJECTIVES: This study aimed to investigate the profile of patients with intracranial aneurysms who underwent endovascular management in the Interventional Neuroradiology Unit at Chris Hani Baragwanath Academic Hospital. Patient demographics, risk factors, indications, aneurysm characteristics and intra-operative complications were studied. METHOD: This was a 3-year retrospective study of all adult patients between 01 January 2018 and 31 January 2021. The Chi-square test was used to compare categorical variables. RESULTS: A total of 77 patients were included in this study. The mean age of the patients was 47 ± 11.6 with a male-to-female ratio of 1:1.8. Hypertension was the most reported risk factor in 27% of patients. There was no statistical correlation between the gender groups according to presentation, multiplicity, aneurysmal size dimensions and locations. According to the presentation, there was statistical significance in ruptured intracranial aneurysms (p = 0.020), neck size dimensions less than 4 mm (p = 0.010), and aneurysms located in the internal cerebral artery (ICA) circulation (p = 0.001). CONCLUSION: The study findings support known parameters including females and anterior circulation aneurysm preponderance, and the low complication risk of endovascular management. Interestingly, intracranial aneurysms presented with rupture at smaller size dimensions. CONTRIBUTION: This study provides valuable insights into intracranial aneurysm characteristics and endovascular management efficacy in a resource-limited setting.
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spelling pubmed-102449672023-06-08 Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital Clarke, Herchel Nefale, Trevor Mngomezulu, Victor SA J Radiol Original Research BACKGROUND: Worldwide, intracranial aneurysms are associated with a high mortality rate. While endovascular management has proven to be the choice of treatment in selected patients, patient demographics and aneurysm characteristics differ between study populations. OBJECTIVES: This study aimed to investigate the profile of patients with intracranial aneurysms who underwent endovascular management in the Interventional Neuroradiology Unit at Chris Hani Baragwanath Academic Hospital. Patient demographics, risk factors, indications, aneurysm characteristics and intra-operative complications were studied. METHOD: This was a 3-year retrospective study of all adult patients between 01 January 2018 and 31 January 2021. The Chi-square test was used to compare categorical variables. RESULTS: A total of 77 patients were included in this study. The mean age of the patients was 47 ± 11.6 with a male-to-female ratio of 1:1.8. Hypertension was the most reported risk factor in 27% of patients. There was no statistical correlation between the gender groups according to presentation, multiplicity, aneurysmal size dimensions and locations. According to the presentation, there was statistical significance in ruptured intracranial aneurysms (p = 0.020), neck size dimensions less than 4 mm (p = 0.010), and aneurysms located in the internal cerebral artery (ICA) circulation (p = 0.001). CONCLUSION: The study findings support known parameters including females and anterior circulation aneurysm preponderance, and the low complication risk of endovascular management. Interestingly, intracranial aneurysms presented with rupture at smaller size dimensions. CONTRIBUTION: This study provides valuable insights into intracranial aneurysm characteristics and endovascular management efficacy in a resource-limited setting. AOSIS 2023-05-26 /pmc/articles/PMC10244967/ /pubmed/37292418 http://dx.doi.org/10.4102/sajr.v27i1.2634 Text en © 2023. The Authors https://creativecommons.org/licenses/by/4.0/Licensee: AOSIS. This work is licensed under the Creative Commons Attribution License.
spellingShingle Original Research
Clarke, Herchel
Nefale, Trevor
Mngomezulu, Victor
Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title_full Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title_fullStr Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title_full_unstemmed Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title_short Endovascular management of intracranial aneurysms at Chris Hani Baragwanath Academic Hospital
title_sort endovascular management of intracranial aneurysms at chris hani baragwanath academic hospital
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10244967/
https://www.ncbi.nlm.nih.gov/pubmed/37292418
http://dx.doi.org/10.4102/sajr.v27i1.2634
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