Cargando…
PM2.5 promotes lung cancer progression through activation of the AhR‐TMPRSS2‐IL18 pathway
Particulate matter 2.5 (PM2.5) is a risk factor for lung cancer. In this study, we investigated the molecular mechanisms of PM2.5 exposure on lung cancer progression. We found that short‐term exposure to PM2.5 for 24 h activated the EGFR pathway in lung cancer cells (EGFR wild‐type and mutant), whil...
Autores principales: | Wang, Tong‐Hong, Huang, Kuo‐Yen, Chen, Chin‐Chuan, Chang, Ya‐Hsuan, Chen, Hsuan‐Yu, Hsueh, Chuen, Liu, Yi‐Tsen, Yang, Shuenn‐Chen, Yang, Pan‐Chyr, Chen, Chi‐Yuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245036/ https://www.ncbi.nlm.nih.gov/pubmed/36975376 http://dx.doi.org/10.15252/emmm.202217014 |
Ejemplares similares
-
The inhibition of lung cancer cell migration by AhR-regulated autophagy
por: Tsai, Chi-Hao, et al.
Publicado: (2017) -
The Landscape of AhR Regulators and Coregulators to Fine-Tune AhR Functions
por: Gargaro, Marco, et al.
Publicado: (2021) -
Coactivator Recruitment of AhR/ARNT1
por: Endler, Alexander, et al.
Publicado: (2014) -
Tumor-Suppressive Functions of the Aryl Hydrocarbon Receptor (AhR) and AhR as a Therapeutic Target in Cancer
por: Elson, Daniel J., et al.
Publicado: (2023) -
Serotonin Modulates AhR Activation by Interfering with CYP1A1-Mediated Clearance of AhR Ligands
por: Manzella, Christopher R., et al.
Publicado: (2020)