Multi‐omic profiling reveals an RNA processing rheostat that predisposes to prostate cancer

Prostate cancer is the most commonly diagnosed malignancy and the third leading cause of cancer deaths. GWAS have identified variants associated with prostate cancer susceptibility; however, mechanistic and functional validation of these mutations is lacking. We used CRISPR‐Cas9 genome editing to in...

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Detalles Bibliográficos
Autores principales: Stentenbach, Maike, Ermer, Judith A, Rudler, Danielle L, Perks, Kara L, Raven, Samuel A, Lee, Richard G, McCubbin, Tim, Marcellin, Esteban, Siira, Stefan J, Rackham, Oliver, Filipovska, Aleksandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245041/
https://www.ncbi.nlm.nih.gov/pubmed/37093546
http://dx.doi.org/10.15252/emmm.202317463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245041/
https://www.ncbi.nlm.nih.gov/pubmed/37093546
http://dx.doi.org/10.15252/emmm.202317463

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