Protein–protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning

The outer membrane (OM) of Gram-negative bacteria is an asymmetric bilayer that protects the cell from external stressors, such as antibiotics. The Mla transport system is implicated in the Maintenance of OM Lipid Asymmetry by mediating retrograde phospholipid transport across the cell envelope. Mla...

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Detalles Bibliográficos
Autores principales: MacRae, Mark R., Puvanendran, Dhenesh, Haase, Max A.B., Coudray, Nicolas, Kolich, Ljuvica, Lam, Cherry, Baek, Minkyung, Bhabha, Gira, Ekiert, Damian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245069/
https://www.ncbi.nlm.nih.gov/pubmed/37100290
http://dx.doi.org/10.1016/j.jbc.2023.104744

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