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Design, synthesis, and biological evaluation with molecular dynamics study of novel pyrazolo[3,4-d]pyrimidine derivatives as anti-cancer agents

In continuation of our efforts to discover new structural chemotypes with significant chemotherapeutic activities, a novel series of pyrazolo[3,4-d]pyrimidine-based compounds linked to a piperazine ring, bearing different aromatic moieties, through different linkages was designed and synthesized as...

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Detalles Bibliográficos
Autores principales:	Shaban, Rania M., Samir, Nermin, Nissan, Yassin M., Abouzid, Khaled A. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245091/ https://www.ncbi.nlm.nih.gov/pubmed/37293475 http://dx.doi.org/10.1039/d3ra00446e

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