STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis

Spermatogenesis defects are important for male infertility; however, the etiology and pathogenesis are still unknown. Herein, we identified two loss-of-function mutations of STK33 in seven individuals with non-obstructive azoospermia. Further functional studies of these frameshift and nonsense mutat...

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Detalles Bibliográficos
Autores principales: Yu, Weiling, Li, Yang, Chen, Hong, Cui, Yiqiang, Situ, Chenghao, Yao, Liping, Zhang, Xiangzheng, Lu, Shuai, Liu, Li, Li, Laihua, Ren, Jie, Guo, Yueshuai, Huo, Zian, Chen, Yu, Li, Haojie, Jiang, Tao, Gu, Yayun, Wang, Cheng, Zhu, Tianyu, Li, Yan, Hu, Zhibin, Guo, Xuejiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245119/
https://www.ncbi.nlm.nih.gov/pubmed/37146716
http://dx.doi.org/10.1016/j.mcpro.2023.100564

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