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CNS4 causes subtype‐specific changes in agonist efficacy and reversal potential of permeant cations in NMDA receptors

The NMDA subtype of glutamate receptor serves as an attractive drug target for the treatment of disorders evolving from hyper‐ or hypoglutamatergic conditions. Compounds that optimize the function of NMDA receptors are of great clinical significance. Here, we present the pharmacological characteriza...

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Detalles Bibliográficos
Autores principales: Boehringer, Seth C., Johnston, Tulia V., Kwapisz, Lina Cortez, VandeVord, Pamela J., Costa, Blaise M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245146/
https://www.ncbi.nlm.nih.gov/pubmed/37283007
http://dx.doi.org/10.1002/prp2.1107