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Association of CYP2C19 Loss-of-Function Metabolizer Status With Stroke Risk Among Chinese Patients Treated With Ticagrelor-Aspirin vs Clopidogrel-Aspirin: A Prespecified Secondary Analysis of a Randomized Clinical Trial

IMPORTANCE: The Clopidogrel With Aspirin in High-Risk Patients With Acute Nondisabling Cerebrovascular Events II (CHANCE-2) trial showed that ticagrelor-aspirin combination therapy reduced the risk of stroke compared with a clopidogrel-aspirin combination among carriers of CYP2C19 loss-of-function (...

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Detalles Bibliográficos
Autores principales:	Xie, Xuewei, Johnston, S. Claiborne, Wang, Anxin, Xu, Qin, Bath, Philip M., Pan, Yuesong, Li, Hao, Lin, Jinxi, Wang, Yilong, Zhao, Xingquan, Li, Zixiao, Jiang, Yong, Liu, Liping, Xu, Anding, Jing, Jing, Meng, Xia, Wang, Yongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Medical Association 2023
Materias:	Original Investigation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245195/ https://www.ncbi.nlm.nih.gov/pubmed/37279000 http://dx.doi.org/10.1001/jamanetworkopen.2023.17037

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