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An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic

Lockdowns are found to be effective against rapidly spreading epidemics like COVID-19. Two downsides to strategies rooted in social distancing and lockdowns are that they adversely affect the economy and prolong the duration of the epidemic. The extended duration observed in these strategies is ofte...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Sreenath, Palathingal, Safvan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245284/
https://www.ncbi.nlm.nih.gov/pubmed/37290500
http://dx.doi.org/10.1016/j.jtbi.2023.111555
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author Balakrishnan, Sreenath
Palathingal, Safvan
author_facet Balakrishnan, Sreenath
Palathingal, Safvan
author_sort Balakrishnan, Sreenath
collection PubMed
description Lockdowns are found to be effective against rapidly spreading epidemics like COVID-19. Two downsides to strategies rooted in social distancing and lockdowns are that they adversely affect the economy and prolong the duration of the epidemic. The extended duration observed in these strategies is often due to the under-utilization of medical facilities. Even though an under-utilized health care system is preferred over an overwhelmed one, an alternate strategy could be to maintain medical facilities close to their capacity, with a factor of safety. We explore the practicality of this alternate mitigation strategy and show that it can be achieved by varying the testing rate. We present an algorithm to calculate the number of tests per day to maintain medical facilities close to their capacity. We illustrate the efficacy of our strategy by showing that it reduced the epidemic duration by 40% in comparison to lockdown-based strategies.
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spelling pubmed-102452842023-06-07 An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic Balakrishnan, Sreenath Palathingal, Safvan J Theor Biol Article Lockdowns are found to be effective against rapidly spreading epidemics like COVID-19. Two downsides to strategies rooted in social distancing and lockdowns are that they adversely affect the economy and prolong the duration of the epidemic. The extended duration observed in these strategies is often due to the under-utilization of medical facilities. Even though an under-utilized health care system is preferred over an overwhelmed one, an alternate strategy could be to maintain medical facilities close to their capacity, with a factor of safety. We explore the practicality of this alternate mitigation strategy and show that it can be achieved by varying the testing rate. We present an algorithm to calculate the number of tests per day to maintain medical facilities close to their capacity. We illustrate the efficacy of our strategy by showing that it reduced the epidemic duration by 40% in comparison to lockdown-based strategies. Elsevier Ltd. 2023-08-21 2023-06-07 /pmc/articles/PMC10245284/ /pubmed/37290500 http://dx.doi.org/10.1016/j.jtbi.2023.111555 Text en © 2023 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Balakrishnan, Sreenath
Palathingal, Safvan
An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title_full An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title_fullStr An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title_full_unstemmed An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title_short An adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
title_sort adaptive testing strategy for efficient utilization of healthcare resources during an epidemic
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245284/
https://www.ncbi.nlm.nih.gov/pubmed/37290500
http://dx.doi.org/10.1016/j.jtbi.2023.111555
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