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Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians

BACKGROUND AND AIMS: Insulin is a temperature-sensitive protein; hence, its potency is highly dependent on appropriate storage. Ideally, insulin should be stored in the refrigerator, but when in use it can be stored at room temperature for up to four weeks. However, room temperatures vary widely acr...

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Autores principales: Pande, Arun K., Thakur, Ashwani K., Kanchan, Arvind, Srivastava, Indu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245316/
https://www.ncbi.nlm.nih.gov/pubmed/37292065
http://dx.doi.org/10.4103/ijem.ijem_437_22
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author Pande, Arun K.
Thakur, Ashwani K.
Kanchan, Arvind
Srivastava, Indu
author_facet Pande, Arun K.
Thakur, Ashwani K.
Kanchan, Arvind
Srivastava, Indu
author_sort Pande, Arun K.
collection PubMed
description BACKGROUND AND AIMS: Insulin is a temperature-sensitive protein; hence, its potency is highly dependent on appropriate storage. Ideally, insulin should be stored in the refrigerator, but when in use it can be stored at room temperature for up to four weeks. However, room temperatures vary widely across regions and countries, and all rural areas of developing countries like India are not electrified. This study explored physicians’ perception of alternative methods for appropriate storage of insulin, such as indigenous storage methods like clay pots. METHODS: A Study was conducted among 188 Indian physicians attending a diabetes conference in December 2018 to evaluate the feasibility of indigenous storage methods. RESULTS: It was observed that although the use of alternate indigenous methods like clay pots was recommended by them, the proportion was low. The awareness of literature on these methods for insulin storage validation was also less than 50%. Owing to the lack of validation studies on indigenous methods, nearly 80% of the physicians felt that they were not confident to recommend them. Besides, the study results highlighted the necessity of conducting an adequate number of validation studies on indigenous methods in the Indian setting, considering their scarcity. CONCLUSION: This is the first time we highlight ethical dilemmas through a study among physicians when they advise non-refrigerator methods for insulin storage, in the event of a lack of electricity supply. It is hoped that results from these studies would highlight ethical dilemmas among physicians and would motivate researchers in this field to conduct studies to validate alternative methods of insulin storage.
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spelling pubmed-102453162023-06-08 Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians Pande, Arun K. Thakur, Ashwani K. Kanchan, Arvind Srivastava, Indu Indian J Endocrinol Metab Original Article BACKGROUND AND AIMS: Insulin is a temperature-sensitive protein; hence, its potency is highly dependent on appropriate storage. Ideally, insulin should be stored in the refrigerator, but when in use it can be stored at room temperature for up to four weeks. However, room temperatures vary widely across regions and countries, and all rural areas of developing countries like India are not electrified. This study explored physicians’ perception of alternative methods for appropriate storage of insulin, such as indigenous storage methods like clay pots. METHODS: A Study was conducted among 188 Indian physicians attending a diabetes conference in December 2018 to evaluate the feasibility of indigenous storage methods. RESULTS: It was observed that although the use of alternate indigenous methods like clay pots was recommended by them, the proportion was low. The awareness of literature on these methods for insulin storage validation was also less than 50%. Owing to the lack of validation studies on indigenous methods, nearly 80% of the physicians felt that they were not confident to recommend them. Besides, the study results highlighted the necessity of conducting an adequate number of validation studies on indigenous methods in the Indian setting, considering their scarcity. CONCLUSION: This is the first time we highlight ethical dilemmas through a study among physicians when they advise non-refrigerator methods for insulin storage, in the event of a lack of electricity supply. It is hoped that results from these studies would highlight ethical dilemmas among physicians and would motivate researchers in this field to conduct studies to validate alternative methods of insulin storage. Wolters Kluwer - Medknow 2023 2023-04-14 /pmc/articles/PMC10245316/ /pubmed/37292065 http://dx.doi.org/10.4103/ijem.ijem_437_22 Text en Copyright: © 2023 Indian Journal of Endocrinology and Metabolism https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Pande, Arun K.
Thakur, Ashwani K.
Kanchan, Arvind
Srivastava, Indu
Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title_full Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title_fullStr Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title_full_unstemmed Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title_short Addressing Challenges in Insulin Storage: An Ethical Dilemma among Physicians
title_sort addressing challenges in insulin storage: an ethical dilemma among physicians
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245316/
https://www.ncbi.nlm.nih.gov/pubmed/37292065
http://dx.doi.org/10.4103/ijem.ijem_437_22
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