Genetic variants of TLR4, including the novel variant, rs5030719, and related genes are associated with susceptibility to clinical malaria in African children

BACKGROUND: Malaria is a deadly disease caused by Plasmodium spp. Several blood phenotypes have been associated with malarial resistance, which suggests a genetic component to immune protection. METHODS: One hundred and eighty-seven single nucleotide polymorphisms (SNPs) in 37 candidate genes were g...

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Detalles Bibliográficos
Autores principales: Ariff, Amir, Song, Yong, Aguilar, Ruth, Nhabomba, Augusto, Manaca, Maria Nelia, Khoo, Siew-Kim, Wiertsema, Selma, Bassat, Quique, Barbosa, Arnoldo, Quintó, Llorenç, Laing, Ingrid A., Guinovart, Caterina, Alonso, Pedro L., Dobaño, Carlota, Le Souëf, Peter, Zhang, Guicheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245343/
https://www.ncbi.nlm.nih.gov/pubmed/37287037
http://dx.doi.org/10.1186/s12936-023-04549-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245343/
https://www.ncbi.nlm.nih.gov/pubmed/37287037
http://dx.doi.org/10.1186/s12936-023-04549-8

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