More efficient and inclusive time-to-event trials with covariate adjustment: a simulation study

Adjustment for prognostic covariates increases the statistical power of randomized trials. The factors influencing the increase of power are well-known for trials with continuous outcomes. Here, we study which factors influence power and sample size requirements in time-to-event trials. We consider...

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Detalles Bibliográficos
Autores principales: Momal, Raphaëlle, Li, Honghao, Trichelair, Paul, Blum, Michael G. B., Balazard, Félix
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245605/
https://www.ncbi.nlm.nih.gov/pubmed/37280655
http://dx.doi.org/10.1186/s13063-023-07375-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245605/
https://www.ncbi.nlm.nih.gov/pubmed/37280655
http://dx.doi.org/10.1186/s13063-023-07375-0

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