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Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach

The probiotic yeast Saccharomyces boulardii (Sb) is a promising chassis to deliver therapeutic proteins to the gut due to Sb’s innate therapeutic properties, resistance to phage and antibiotics, and high protein secretion capacity. To maintain therapeutic efficacy in the context of challenges such a...

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Detalles Bibliográficos
Autores principales:	Durmusoglu, Deniz, Al’Abri, Ibrahim, Li, Zidan, Islam Williams, Taufika, Collins, Leonard B., Martínez, José L., Crook, Nathan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245609/ https://www.ncbi.nlm.nih.gov/pubmed/37287064 http://dx.doi.org/10.1186/s12934-023-02117-y

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