Infection-induced epilepsy is caused by increased expression of chondroitin sulfate proteoglycans in hippocampus and amygdala

Alterations in the extracellular matrix (ECM) are common in epilepsy, yet whether they are cause or consequence of disease is unknow. Using Theiler’s virus infection model of acquired epilepsy we find de novo expression of chondroitin sulfate proteoglycans (CSPGs), a major ECM component, in dentate...

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Detalles Bibliográficos
Autores principales: Patel, Dipan C., Swift, Nathaniel, Tewari, Bhanu P., Browning, Jack L., Prim, Courtney, Chaunsali, Lata, Kimbrough, Ian, Olsen, Michelle L., Sontheimer, Harald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245664/
https://www.ncbi.nlm.nih.gov/pubmed/37292901
http://dx.doi.org/10.1101/2023.05.16.541066

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