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VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities
The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without a functional virB gene, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional silencing mediated by the nucleoid struct...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245682/ https://www.ncbi.nlm.nih.gov/pubmed/37293012 http://dx.doi.org/10.1101/2023.05.16.541010 |