VirB, a key transcriptional regulator of Shigella virulence, requires a CTP ligand for its regulatory activities

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The VirB protein, encoded by the large virulence plasmid of Shigella spp., is a key transcriptional regulator of virulence genes. Without a functional virB gene, Shigella cells are avirulent. On the virulence plasmid, VirB functions to offset transcriptional silencing mediated by the nucleoid struct...

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Detalles Bibliográficos
Autores principales: Gerson, Taylor M., Ott, Audrey M., Karney, Monika MA., Socea, Jillian N., Ginete, Daren R., Iyer, Lakshminarayan M., Aravind, L., Gary, Ronald K., Wing, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245682/
https://www.ncbi.nlm.nih.gov/pubmed/37293012
http://dx.doi.org/10.1101/2023.05.16.541010
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