Cargando…

The small acid-soluble proteins of Clostridioides difficile regulate sporulation in a SpoIVB2-dependent manner

Clostridioides difficile is a pathogen whose transmission relies on the formation of dormant endospores. Spores are highly resilient forms of bacteria that resist environmental and chemical insults. In recent work, we found that C. difficile SspA and SspB, two small acid-soluble proteins (SASPs), pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nerber, Hailee N., Baloh, Marko, Sorg, Joseph A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245694/ https://www.ncbi.nlm.nih.gov/pubmed/37292792 http://dx.doi.org/10.1101/2023.05.17.541253

Ejemplares similares

The small acid-soluble proteins of Clostridioides difficile are important for UV resistance and serve as a check point for sporulation
por: Nerber, Hailee N., et al.
Publicado: (2021)

Solution Structure of SpoIVB Reveals Mechanism of PDZ Domain-Regulated Protease Activity
por: Xie, Xie, et al.
Publicado: (2019)

Role of SpoIVA ATPase Motifs during Clostridioides difficile Sporulation
por: Benito de la Puebla, Hector, et al.
Publicado: (2020)

Clostridioides difficile Biology: Sporulation, Germination, and Corresponding Therapies for C. difficile Infection
por: Zhu, Duolong, et al.
Publicado: (2018)

Butyrate enhances Clostridioides difficile sporulation in vitro
por: Baldassare, Michelle A., et al.
Publicado: (2023)

A network of small RNAs regulates sporulation initiation in Clostridioides difficile
por: Fuchs, Manuela, et al.
Publicado: (2023)

Impact of deoxycholate on Clostridioides difficile growth, toxin production, and sporulation
por: Usui, Yukino, et al.
Publicado: (2020)

c-di-GMP Inhibits Early Sporulation in Clostridioides difficile
por: Edwards, Adrianne N., et al.
Publicado: (2021)

Spo0A Suppresses sin Locus Expression in Clostridioides difficile
por: Dhungel, Babita Adhikari, et al.
Publicado: (2020)

Functional genomics reveals that Clostridium difficile Spo0A coordinates sporulation, virulence and metabolism
por: Pettit, Laura J, et al.
Publicado: (2014)

Inducible Expression of spo0A as a Universal Tool for Studying Sporulation in Clostridium difficile
por: Dembek, Marcin, et al.
Publicado: (2017)

SpoVG Is Necessary for Sporulation in Bacillus anthracis
por: Chen, Meng, et al.
Publicado: (2020)

Modeling Curvature-Dependent Subcellular Localization of the Small Sporulation Protein SpoVM in Bacillus subtilis
por: Wasnik, Vaibhav, et al.
Publicado: (2015)

A sporulation signature protease is required for assembly of the spore surface layers, germination and host colonization in Clostridioides difficile
por: Marini, Eleonora, et al.
Publicado: (2023)

CD25890, a conserved protein that modulates sporulation initiation in Clostridioides difficile
por: Martins, Diogo, et al.
Publicado: (2021)

Response Regulator CD1688 Is a Negative Modulator of Sporulation in Clostridioides difficile
por: Kempher, Megan L., et al.
Publicado: (2022)

SpoIVA-SipL Complex Formation Is Essential for Clostridioides difficile Spore Assembly
por: Touchette, Megan H., et al.
Publicado: (2019)

Impact of CodY protein on metabolism, sporulation and virulence in Clostridioides difficile ribotype 027
por: Daou, Nadine, et al.
Publicado: (2019)

Cortex synthesis during Bacillus subtilis sporulation depends on the transpeptidase activity of SpoVD
por: Bukowska-Faniband, Ewa, et al.
Publicado: (2013)

SPO73 and SPO71 Function Cooperatively in Prospore Membrane Elongation During Sporulation in Saccharomyces cerevisiae
por: Parodi, Emily M., et al.
Publicado: (2015)

Epigenomic characterization of Clostridioides difficile finds a conserved DNA methyltransferase that mediates sporulation and pathogenesis
por: Oliveira, Pedro H., et al.
Publicado: (2019)

From Root to Tips: Sporulation Evolution and Specialization in Bacillus subtilis and the Intestinal Pathogen Clostridioides difficile
por: Ramos-Silva, Paula, et al.
Publicado: (2019)

Combined and Distinct Roles of Agr Proteins in Clostridioides difficile 630 Sporulation, Motility, and Toxin Production
por: Ahmed, Ummey Khalecha Bintha, et al.
Publicado: (2020)

Factors and Conditions That Impact Electroporation of Clostridioides difficile Strains
por: Bhattacharjee, Disha, et al.
Publicado: (2020)

Interactions Between Clostridioides difficile and Fecal Microbiota in in Vitro Batch Model: Growth, Sporulation, and Microbiota Changes
por: Horvat, Sabina, et al.
Publicado: (2018)

Gut associated metabolites and their roles in Clostridioides difficile pathogenesis
por: Aguirre, Andrea Martinez, et al.
Publicado: (2022)

The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system
por: Edwards, Adrianne N., et al.
Publicado: (2023)

The RgaS-RgaR two-component system promotes Clostridioides difficile sporulation through a small RNA and the Agr1 system
por: Edwards, Adrianne N., et al.
Publicado: (2023)

Regulation of Clostridium difficile Spore Formation by the SpoIIQ and SpoIIIA Proteins
por: Fimlaid, Kelly A., et al.
Publicado: (2015)

The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties
por: Clark, Andrew E., et al.
Publicado: (2022)

Repurposing epigenetic inhibitors to target the Clostridioides difficile-specific DNA adenine methyltransferase and sporulation regulator CamA
por: Zhou, Jujun, et al.
Publicado: (2021)

SPO24 Is a Transcriptionally Dynamic, Small ORF-Encoding Locus Required for Efficient Sporulation in Saccharomyces cerevisiae
por: Hurtado, Sara, et al.
Publicado: (2014)

SpoVG is an important regulator of sporulation and affects biofilm formation by regulating Spo0A transcription in Bacillus cereus 0–9
por: Huang, Qiubin, et al.
Publicado: (2021)

Visualization and functional dissection of coaxial paired SpoIIIE channels across the sporulation septum
por: Shin, Jae Yen, et al.
Publicado: (2015)

Morphogenic Protein RodZ Interacts with Sporulation Specific SpoIIE in Bacillus subtilis
por: Muchová, Katarína, et al.
Publicado: (2016)

Effect of tcdR Mutation on Sporulation in the Epidemic Clostridium difficile Strain R20291
por: Girinathan, Brintha P., et al.
Publicado: (2017)

Emergence of a non-sporulating secondary phenotype in Clostridium (Clostridioides) difficile ribotype 078 isolated from humans and animals
por: Connor, M. C., et al.
Publicado: (2019)

Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile
por: Boudry, Pierre, et al.
Publicado: (2021)

C. difficile 630Δerm Spo0A Regulates Sporulation, but Does Not Contribute to Toxin Production, by Direct High-Affinity Binding to Target DNA
por: Rosenbusch, Katharina E., et al.
Publicado: (2012)

Identification and Functional Characterization of Two Homologous SpoVS Proteins Involved in Sporulation of Bacillus thuringiensis
por: Liu, Xinlu, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qb1im7c4brtf3c6p1oghvsksot