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p300 Is an Obligate Integrator of Combinatorial Transcription Factor Inputs

Transcription coactivators are proteins or protein complexes that mediate transcription factor (TF) function. However, they lack DNA binding capacity, prompting the question of how they engage target loci. Three non-exclusive hypotheses have been posited: coactivators are recruited by complexing wit...

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Detalles Bibliográficos
Autores principales: Ferrie, John J., Karr, Jonathan P., Graham, Thomas G.W., Dailey, Gina M., Zhang, Gloria, Tjian, Robert, Darzacq, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245728/
https://www.ncbi.nlm.nih.gov/pubmed/37292840
http://dx.doi.org/10.1101/2023.05.18.541220