CRISPR-based engineering of RNA viruses

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CRISPR RNA-guided endonucleases have enabled precise editing of DNA. However, options for editing RNA remain limited. Here, we combine sequence-specific RNA cleavage by CRISPR ribonucleases with programmable RNA repair to make precise deletions and insertions in RNA. This work establishes a new reco...

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Detalles Bibliográficos
Autores principales: Nemudryi, Artem, Nemudraia, Anna, Nichols, Joseph E, Scherffius, Andrew M, Zahl, Trevor, Wiedenheft, Blake
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245796/
https://www.ncbi.nlm.nih.gov/pubmed/37292641
http://dx.doi.org/10.1101/2023.05.19.541219
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