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Ablation of Sam50 is associated with fragmentation and alterations in metabolism in murine and human myotubes

The Sorting and Assembly Machinery (SAM) Complex is responsible for assembling β-barrel proteins in the mitochondrial membrane. Comprising three subunits, Sam35, Sam37, and Sam50, the SAM complex connects the inner and outer mitochondrial membranes by interacting with the mitochondrial contact site...

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Detalles Bibliográficos
Autores principales: Shao, Bryanna, Killion, Mason, Oliver, Ashton, Vang, Chia, Zeleke, Faben, Neikirk, Kit, Vue, Zer, Garza-Lopez, Edgar, Shao, Jian-qiang, Mungai, Margaret, Lam, Jacob, Williams, Qiana, Altamura, Christopher T., Whiteside, Aaron, Kabugi, Kinuthia, McKenzie, Jessica, Koh, Alice, Scudese, Estevão, Vang, Larry, Marshall, Andrea G., Crabtree, Amber, Tanghal, Janelle I., Stephens, Dominique, Koh, Ho-Jin, Jenkins, Brenita C., Murray, Sandra A., Cooper, Anthonya T., Williams, Clintoria, Damo, Steven M., McReynolds, Melanie R., Gaddy, Jennifer A., Wanjalla, Celestine N., Beasley, Heather K., Hinton, Antentor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245823/
https://www.ncbi.nlm.nih.gov/pubmed/37292887
http://dx.doi.org/10.1101/2023.05.20.541602