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DNA methylation-environment interactions in the human genome

Previously we showed that a massively parallel reporter assay, mSTARR-seq, could be used to simultaneously test for both enhancer-like activity and DNA methylation-dependent enhancer activity for millions of loci in a single experiment (Lea et al., 2018). Here we apply mSTARR-seq to query nearly the...

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Detalles Bibliográficos
Autores principales: Johnston, Rachel A., Aracena, Katherine A., Barreiro, Luis B., Lea, Amanda J., Tung, Jenny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245841/
https://www.ncbi.nlm.nih.gov/pubmed/37293015
http://dx.doi.org/10.1101/2023.05.19.541437