Basolateral Amygdala Corticotrophin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory

Inhibiting the actin motor ATPase nonmuscle myosin II (NMII) with blebbistatin (Blebb) in the basolateral amgydala (BLA) depolymerizes actin, resulting in an immediate, retrieval-independent disruption of methamphetamine (METH)-associated memory. The effect is highly selective, as NMII inhibition ha...

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Detalles Bibliográficos
Autores principales: Hafenbreidel, Madalyn, Briggs, Sherri B., Arza, Meghana, Bonthu, Shalakha, Fisher, Cadence, Tiller, Annika, Hall, Alice B., Reed, Shayna, Mayorga, Natasha, Lin, Li, Khan, Susan, Cameron, Michael D., Rumbaugh, Gavin, Miller, Courtney A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245849/
https://www.ncbi.nlm.nih.gov/pubmed/37292925
http://dx.doi.org/10.1101/2023.05.22.541732

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