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Long-range repression by ecdysone receptor on complex enhancers of the insulin receptor gene

The insulin signaling pathway is evolutionarily conserved throughout metazoans, playing key roles in development, growth, and metabolism. Misregulation of this pathway is associated with a multitude of disease states including diabetes, cancer, and neurodegeneration. Genome-wide association studies...

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Detalles Bibliográficos
Autores principales: Thompson, Katie, Suber, Will, Nicholas, Rachel, Arnosti, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10245858/
https://www.ncbi.nlm.nih.gov/pubmed/37293119
http://dx.doi.org/10.1101/2023.05.23.541945